BioTuring's Blog - Data analysis made easy. For biologists, especially.
Data analysis made easy. For biologists, especially.
Explore 10X Visium Spatial Transcriptomics data at ease with BioTuring Browser
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Cells don’t function independently. They belong to a complex and interconnected network. This makes gene expression profiling of individual cells not enough for understanding their activities and crosstalk in the tissue context.  Like a marriage between imaging and RNA sequencing, Spatial Transcriptomics is a revolutionized method to map gene activity […]

A tiny world inside non-small cell lung cancer revealed by single-cell omics: 35 cell types, and their marker genes
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Take a non-small cell lung tumor. What do we see? To answer this challenging question, a lot of single-cell omics experiments have been conducted, yielding significant insights into the heterogeneity of non-small cell lung cancer (NSCLC) microenvironment. While each successfully characterizes a facet of this ecosystem, until now no work […]

Immunoglobulin genes up-regulated in lung adenocarcinoma infiltrating T cells: A report from BioTuring lung cancer single cell database
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Highlights: In every biology textbook, expression of the B cell receptor (BCR) defines B cells, and the T cell receptor (TCR) defines T cells. However, in 2019, Ahmed et al. discovered a strange cell population in Type I Diabetes that coexpresses the BCR and TCR, and key lineage markers of […]

BioVinci: high-dimensional data visualization made easy for biologists
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“How to extract the biology behind this huge matrix of thousands of rows and columns?”  Large numbers of data points hold valuable biological stories yet are tricky to graph and analyze. Imagine you had the data for 1000 features and observations, your mind would be full of questions, wondering how […]

Single-cell analysis of CD8+ T cells in immune checkpoint blockade: some reproducible insights from BioTuring Database
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Cancer treatment, as challenging as it sounds, has been revolutionized by recent advances in immune checkpoint blockade (ICB) therapies, which use monoclonal antibodies (mAb) to block the suppressive immune checkpoints, helping the patient’s immune system to kill cancer cells. However, despite several clinical case studies of success, some patients still […]

Interactive CITE-Seq data analysis with BioTuring Browser
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Nominated as Method of the year by Nature in 2019, single-cell multimodal omics has enabled scientists to uncover many facets of the cells by simultaneously measuring multiple modalities in one single-cell experiment. One candidate for multimodal analysis is CITE-Seq, a technique that layers cell surface protein information on top of […]