dimensionality reduction Archives - BioTuring's Blog
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Tag Archives: dimensionality reduction

scRNA-Seq Cell Type Annotation: Common Approaches and Tools
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scrna seq cell type annotation talk2data

Assigning cell type identity to cells is a basic yet vital step required in single-cell RNA Sequencing data analysis (scRNA-Seq), often done after dimensionality reduction and scRNA-Seq clustering . If you have successfully captured informative clusters, it’s time to face an even harder challenge: identify what cell type or cell […]

The Essence of scRNA-Seq Clustering: Why and How to Do it Right
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Clustering is The Microscope For scRNA-Seq data In previous posts, we have walked you through important steps in analyzing your single-cell RNA sequencing (scRNA-Seq) data, including data visualization and normalization. This time, let’s explore the next logical step in the data analysis pipeline: clustering scRNA-Seq data.  What is scRNA-Seq clustering?  […]

Comparing UMAP vs t-SNE in Single-cell RNA-Seq Data Visualization, Simply Explained
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umap vs tsne global structure

How to Make Sense of Single-cell RNA Sequencing Data? Less is More Thanks to single-cell RNA sequencing (scRNA-seq), researchers are blessed with a trove of information. Yet, this blessing is also a curse in data visualization and further analysis! Since each cell is described by its gene expression profile, our […]