RNA-seq data analysis Archives - BioTuring's Blog
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Category Archives: RNA-seq data analysis

Comparing UMAP vs t-SNE in Single-cell RNA-Seq Data Visualization, Simply Explained
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umap vs tsne global structure

How to Make Sense of Single-cell RNA Sequencing Data? Less is More Thanks to single-cell RNA sequencing (scRNA-seq), researchers are blessed with a trove of information. Yet, this blessing is also a curse in data visualization and further analysis! Since each cell is described by its gene expression profile, our […]

Dissect a spatial transcriptomics brain dataset with BBrowser: the human prefrontal cortex by Maynard et al. (2021)
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Spatial Transcriptomics Brain Data Is In Demand The spatial gene expression contributes significantly to brain morphology, physiology, and connectivity. However, obtaining spatial transcriptomics brain data has long been a technical challenge. Recently, with continuous breakthroughs in spatial transcriptomics sequencing technique and data analysis tools, spatial human brain single cell RNA-Seq […]

Zooming in the intratumoral heterogeneity of liver cancer with BBrowser single cell database
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intratumoral heterogeneity - liver cancer cell composition

Introduction  Why are tumors so resilient against available cancer therapies? One answer lies in intratumoral heterogeneity.  Intratumoral heterogeneity describes the diversity in tumor cell populations. Cancer cells exhibit startling distinctions in their types, shape, metabolic activities, transcriptomic profiles, and more. The causes of intratumoral heterogeneity are both heritable (clonal expansion […]

BioTuring Browser: the software to resolve major challenges in single-cell RNA-seq data analysis
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Single-cell RNA-seq technologies have opened up a completely new era for transcriptomic studies. For the first time ever, scientists can look at individual transcriptomic profiles of millions of cells, and better understand how each cell functions in a tissue. Yet science is confronting bigger challenges analyzing these massive amounts of […]